Extramedullary leukemia in children presenting with proptosis

Extramedullary leukemia in children presenting with proptosis

BACKGROUND We highlight the orbital manifestations of acute myeloid leukemia and the role of peripheral blood smear in the diagnosis of these cases. A total of 12 patients who presented with proptosis and were subsequently diagnosed to have acute myeloid leukemia based on incision biopsy or peripheral blood smear were included in the study. RESULTS A retrospective review of all cases of acute...

Chronic Myeloid Leukemia presenting with extramedullary disease as gingival hyperplasia

Frontoethmoidal mucocele presenting as proptosis.

To cite: Shang Kuan W-C, Chi C-C. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013202733 DESCRIPTION A 34-year-old man suffered from itching, burning and a foreign body sensation in his left eye for 6 months prior to his first ophthalmology clinic visit, where eye drops were prescribed for presumed keratitis without obvious improvement. Furthermore, his left e...

Extramedullary Hematopoiesis in a Patient with Transfusion Dependent Beta-Thalassemia Presenting with Cord Compression

Extramedullary hematopoiesis (EMH) is a physiological compensatory phenomenon occurring in many hemolytic anemias including thalassemia. Besides transfusion, radiotherapy, surgery or a combination of these modalities, hydroxyurea (HU) as an optimal treatment has been described occasionally. We described a case of beta-thalassemia major who has been on regular blood transfusion and developed EMH...

Orbital myeloid sarcoma presenting as massive proptosis.

A 10-year-old boy presented with right proptosis for 8 months. The eyeball was grossly pushed down, with diffuse corneal haze and non-reactive pupil. Systemic examination was normal. Previous investigations in another centre included a computerized tomography scan, which showed a well-defined enhancing retro-bulbar mass, a non-contributory fine needle aspiration cytology and a biopsy showing fi...